Sequence alignment

Consensus key (see documentation for details)
* - single, fully conserved residue
: - conservation of strong groups
. - conservation of weak groups
  - no consensus


CLUSTAL W (1.81) multiple sequence alignment


GENPEPT_7595954      -----------------MAFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAK
GENPEPT_1724118      -----------------MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMTENCLDAK
GENPEPT_466462       -----------------MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAK
GENPEPT_3192877      ---------------MAEYLQPGVIRKLDEVVVNRIAAGEIIQRPANALKELLENSLDAQ
GENPEPT_825572       --------------------MSLRIKALDASVVNKIAAGEIIISPVNALKEMMENSIDAN
GENPEPT_3880333      MWHCGYRTRNCDEFSKIEFSLMGLIQRLPQDVVNRMAAGEVLARPCNAIKELVENSLDAG
                                             *: *   ***::****::  * **:**: **.:** 

GENPEPT_7595954      STNIQVVVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLASISTYGFRGEA
GENPEPT_1724118      STNIQVIVREGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLAMISTYGFRGEA
GENPEPT_466462       STSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEA
GENPEPT_3192877      STHIQVQVKAGGLKLLQIQDNGTGIRREDLAIVCERFTTSKLTRFEDLSQIATFGFRGEA
GENPEPT_825572       ATMIDILVKEGGIKVLQITDNGSGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEA
GENPEPT_3880333      ATEIMVNMQNGGLKLLQVSDNGKGIEREDFALVCERFATSKLQKFEDLMHMKTYGFRGEA
                     :* * : :: **:*::*: ***.**.: *: ::****:****  ****  : *:******

GENPEPT_7595954      LASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRR
GENPEPT_1724118      LASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRK
GENPEPT_466462       LASISHVAHVTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRR
GENPEPT_3192877      LASISHVAHLSIQTKTAKEKCGYKATYADGKLQGQPKPCAGNQGTIICIEDLFYNMPQRR
GENPEPT_825572       LASISHVARVTVTTKVKEDRCAWRVSYAEGKMLESPKPVAGKDGTTILVEDLFFNIPSRL
GENPEPT_3880333      LASLSHVAKVNIVSKRADAKCAYQANFLDGKMTADTKPAAGKNGTCITATDLFYNLPTRR
                     ***:****::.: :*  . :*.::..: :**:   .** **::** *   ***:*:  * 

GENPEPT_7595954      KALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNA
GENPEPT_1724118      KALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNA
GENPEPT_466462       KALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSVFGNA
GENPEPT_3192877      QALRSPAEEFQRLSEVLARYAVHNPRVGFTLRKQGDAQPALRTPVASSRSENIRIIYGAA
GENPEPT_825572       RALRSHNDEYSKILDVVGRYAIHSKDIGFSCKKFGDSNYSLSVKPSYTVQDRIRTVFNKS
GENPEPT_3880333      NKMTTHGEEAKMVNDTLLRFAIHRPDVSFALRQ--NQAGDFRTKGDGNFRDVVCNLLGRD
                     . : .  :*   : :.: *:::*   :.*: ::  :    . .    .  : :  : .  

GENPEPT_7595954      VSRELIEVG-CEDKTLAFK-MNGYISNANYSVKKCIF----------LLFINHRLVESAA
GENPEPT_1724118      VSRELIEVG-CEDKTLAFK-MNGYISNANYSVKKCIF----------LLFINHRLVESAA
GENPEPT_466462       VSRELIEIG-CEDKTLAFK-MNGYISNANYSVKKCIF----------LLFINHRLVESTS
GENPEPT_3192877      ISKELLEFS-HRDEVYKFE-AECLITQVNYSAKKCQM----------LLFINQRLVESTA
GENPEPT_825572       VASNLITFHISKVEDLNLESVDGKVCNLNFISKKSISP---------IFFINNRLVTCDL
GENPEPT_3880333      VADTILPLS-LNSTRLKFT-FTGHISKPIASATAAIAQNRKTSRSFFSVFINGRSVRCDI
                     ::  :: .   .     :      : :     . .             .*** * * .  

GENPEPT_7595954      LRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILQRVQQHIE
GENPEPT_1724118      LKKAIEAVYAAYLPKNTHPFLYLILEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIE
GENPEPT_466462       LRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIE
GENPEPT_3192877      LRTSVDSIYATYLPRGHHPFVYMSLTLPPQNLDVNVHPTKHEVHFLYQEEIVDSIKQQVE
GENPEPT_825572       LRRALNSVYSNYLPKGNRPFIYLGIVIDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLH
GENPEPT_3880333      LKHPIDEVLG--ARQLHAQFCALHLQIDETRIDVNVHPTKNSVIFLEKEEIIEEIRAYFE
                     *: .:: : .    :    *  : : :    :********..* ** ::.*:: :   ..

GENPEPT_7595954      SKLLGSNSSRMYFTQTLLPGLAG------PSGEAARPTTGVASSSTSGSGDKVYAYQMVR
GENPEPT_1724118      SKLLGSNSSRMYFTQTLLPGLAG------PSGEAVKSTTGIASSSTSGSGDKVHAYQMVR
GENPEPT_466462       SKLLGSNSSRMYFTQTLLPGLAG------PSGEMVKSTTSLTSSSTSGSSDKVYAHQMVR
GENPEPT_3192877      ARLLGSNATRTFYKQLRLPGAP-----------------DLDETQLADKTQRIYPKEMVR
GENPEPT_825572       AELSAIDTSRTFKASSISTNKPESLIPFNDTIESDRNRKSLRQAQVVENSYTTANSQLRK
GENPEPT_3880333      KVIGEIFGFEALDVEKPEEEQPD--------IENLVMIPMSQSLKSIEAIRKPDTKPEFK
                       :      .    .      .                    . .              :

GENPEPT_7595954      TDSRDQKLDAFLQPVSSLVPSQPQDPAPVRGARTEGSPERATREDEEMLALPAPAEAAAE
GENPEPT_1724118      TDSRDQKLDAFMQPVSRRLPSQPQD--PVPGNRTEGSPEKAMQKDQEISELPAPMEAAAD
GENPEPT_466462       TDSREQKLDAFLQPLSKPLSSQPQ--AIVTEDKTDISSGRARQQDEEMLELPAPAEVAAK
GENPEPT_3192877      TDSTEQKLDKFLAPLVK-------------------------------------------
GENPEPT_825572       AKRQENKLVRIDASQAKITSFLSSS--QQFNFEGSSTKRQLSEPKVTNVSHSQEAEKLTL
GENPEPT_3880333      SSPSAWKSDKKRVDYMEVRTDAKERKIDEFVTRGGAVGPTTSNDDIFGGSGILKRARTED
                     :.    *                                                     

GENPEPT_7595954      SENLERESLMETSDAAQKAAPTSSPGSSRKRHREDSDVEMVENASGKEMTAACYPRRRII
GENPEPT_1724118      SASLERESVIGASEVVAPQRHPSSPGSSRKRHPEDSDVEMMENDSRKEMTAACYPRRRII
GENPEPT_466462       NQSLEGDTTKGTSEMSEKRGPTSS--NPRKRHREDSDVEMVEDDSRKEMTAACTPRRRII
GENPEPT_3192877      ----------------SDSGVSSSSSQEASRLPEES------------FRVTAAKKSREV
GENPEPT_825572       NESEQPRDANTINDNDLKDQPKKKQKLGDYKVPSIADDEKNALPISKDGYIRVPKERVNV
GENPEPT_3880333      STGGEKEPEDLNTDFDDVSMVSLVSTADGRRLNESQD-----LGEDDDVDFEYGKTHREF
                                                   :  .                         .

GENPEPT_7595954      NLTSVLSLQEEISERCHETLREILRNHSFVGCVNPQW--ALAQHQTKLYLLNTTKLSEEL
GENPEPT_1724118      NLTSVLSLQEEINDRGHETLREMLRNHTFVGCVNPQW--ALAQHQTKLYLLNTTKLSEEL
GENPEPT_466462       NLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQW--ALAQHQTKLYLLNTTKLSEEL
GENPEPT_3192877      RLSSVLDMRKRVERQCSVQLRSTLKNLVYVGCVDERR--ALFQHETRLYMCNTRSFSEEL
GENPEPT_825572       NLTSIKKLREKVDDSIHRELTDIFANLNYVGVVDEERRLAAIQHDLKLFLIDYGSVCYEL
GENPEPT_3880333      HFESIEVLRKEIIANSSQSLREMFKTSTFVGSINVKQ--VLIQFGTSLYHLDFSTVLREF
                     .: *:  :::.:       * . : .  :** :: .   .  *.   *:  :  ..  *:

GENPEPT_7595954      FYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEDDGPKEGLA-----EYIVEF
GENPEPT_1724118      FYQILIYDFANFGVLRLPEPAPLFDFAMLALDSPESGWTEEDGPKEGLA-----EYIVEF
GENPEPT_466462       FYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLA-----EYIVEF
GENPEPT_3192877      FYQRMIYEFQNCSEITICPPLPLKELLILSLESRAAGWTPEDEDKAELA-----DGAADI
GENPEPT_825572       FYQIGLTDFANFGKINLQSTNVSDDIVLYNLLSEFDELN-DDASK---------EKIISK
GENPEPT_3880333      FYQISVFSFGNYGSYRLDE-EPPAIIEILELLGELSTREPNYAAFEVFANVENRFAAEKL
                     ***  : .* * .   :        : :  * .       :                 . 

GENPEPT_7595954      LKKKAEMLADYFSVEIDEEGN--------LIGLPLLIDSYVPPLEGLPIFILRLATEVNW
GENPEPT_1724118      LKKKAKMLADYFSVEIDEEGN--------LIGLPLLIDSYVPPLEGLPIFILRLATEVNW
GENPEPT_466462       LKKKAEMLADYFSLEIDEEGN--------LIGLPLLIDNYVPPLEGLPIFILRLATEVNW
GENPEPT_3192877      LLKKAPIMREYFGLRISEDGM--------LESLPSLLHQHRPCVAHLPVYLLRLATEVDW
GENPEPT_825572       IWDMSSMLNEYYSIELVNDGLDNDLKSVKLKSLPLLLKGYIPSLVKLPFFIYRLGKEVDW
GENPEPT_3880333      LAEHADLLHDYFAIKLDQLENGR----LHITEIPSLVHYFVPQLEKLPFLIATLVLNVDY
                     : . : :: :*:.:.: :           :  :* *:. . * :  **. :  *  :*::

GENPEPT_7595954      DEEKECFESLSKECAMFYSIRKQYILEESTLSGQQSDMPGSTSKPWKWT--VEHIIYKAF
GENPEPT_1724118      DEE-ECFESLSKECAVFYSIRKQYILEESALSGQQSDMPGSPSKPWKWT--VEHIIYKAF
GENPEPT_466462       DEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWT--VEHIVYKAL
GENPEPT_3192877      EQETRCFETFCRETARFY--------------AQLDWREGATAVFSRWT--MEHVLFPAF
GENPEPT_825572       EDEQECLDGILREIALLYIPDMVPKVDTSDASLSEDEKAQFINRKEHISSLLEHVLFPCI
GENPEPT_3880333      DDEQNTFRTICRAIGDLFTLDTN---------FITLDKKISAFSATPWKTLIKEVLMPLV
                     ::* . :  : :  . ::                              .  ::.::   .

GENPEPT_7595954      RSHLLPPKHFTEDGNVLQLANLPDLYKVFERC--
GENPEPT_1724118      RSHLLPPKHFTEDGNVLQLANLPDLCKVFERC--
GENPEPT_466462       RSHILPPKHFTEDGNILQLANLPDLYKVFERC--
GENPEPT_3192877      KKYLLPPR---IKDQIYELTNLPTLYKVFERC--
GENPEPT_825572       KRRFLAPRHILKD--VVEIANLPDLYKVFERC--
GENPEPT_3880333      KRKFIPPEHFKQAGVIRQLADSHDLYKVFERCGT
                     :  ::.*.       : ::::   * ******