CD:

pfam01119,   CD-Search result with query-sequence added

Description:DNA_mis_repair, DNA mismatch repair protein. Also known as the mutL/hexB/PMS1 family.
Source:Pfam[US], Pfam[UK]

 This CD alignment includes 3D structure. To display structure, download Cn3D v3.0!
showing sequences
Aligned chains
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Text Display		 FASTA with gaps
Phylip format		 Conservation color threshold: 
Alignment width:  
                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|
consensus    1 GTTVEVRDLFYNLPVRRKFLKSPKKEFRKILDLLQRYALIHPNVSFSLTKEG--KALLQL 58
query      147 GTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQG--ETVADV 204
1B63_A     144 GTTLEVLDLFYNTPARRKFLRTEKTEFNHIDEIIRRIALARFDVTINLSHNG--KIVRQY 201
gi 8039787 159 GTVVRVEQLFENFPARKRFLGRQSAETTLCRSALIDVSLAHHPVEFRFTVDGthKLTLLS 218
gi 8928214 141 GTIVDVTKIFHNFPARKRFLKQEPIETKMCLKVLEEKIITHPEINFEIN-LN--QKLRKI 197
gi 3914081 141 GTEVEVRDLFFNLPVRRKFLKKEDTERRKVLELIKEYALTNPEVEFTLFSEG--RETLKL 198
gi 3914082 141 GTEVEVYDLFFNLPARKKFLRKEDTERRKITELVKEYAITNPQVDFHLFSEG--KETLNL 198
gi 8928224 141 GTTVEVRDLFFNLPVRRKSLKSSAIELRMCREMFERFVLVRNDVDFVFTSDG--KIVHSF 198
gi 123083  142 GTKVCVEDLFFNTPARLKYMKSQQAELSHIIDIVNRLGLAHPEISFSLISDG--KEMTRT 199
gi 1709188 141 GTEIVVSNLFFNTPARLKYMKTVHTELGNITDVVNRIALAHPEVSIRLRHHG--KNLLQT 198

                       70        80        90       100       110       120
               ....*....|....*....|....*....|....*....|....*....|....*....|
consensus   59 KTSP--S-SLKERIRSVFGTAVLKNLIPF--EEKDGDFRIEG-FISSPNVSR-SSRDRQF 111
query      205 RTLP--NaSTVDNIRSIFGNAVSRELIEIgcEDKTLAFKMNG-YISNANYSV--KKCIFL 259
1B63_A     202 RAVPegG-QKERRLGAICGTAFLEQALAI--EWQHGDLTLRG-WVADPNHTTpALAEIQY 257
gi 8039787 219 QQTR--K-DRCLETQMLKGDPALFHTIEG--G--DCSFHFHLvLSEPAICRR--ERRGIF 269
gi 8928214 198 YFK---E-SLIDRVQNVYGNVIENNKFRV--LKKEHDNIKIEiFLAPDNFSK-KSKRHIK 250
gi 3914081 199 KKS-----SLKERVEEVFQTKTEELYAER--E--GITLRA---FVSRNQRQG-----KYY 241
gi 3914082 199 KKK-----DLKGRIEEIFESIFEEESSER--E--GIKVRA---FISRNQKRG-----KYY 241
gi 8928224 199 PRT---Q-NIFERALLILEDLR-KGYITF--EEELSGLRIKG-IVSSREVTR-SSRTGEY 249
gi 123083  200 AGT---G-QLRQAIAGIYGLVSAKKMIEI--ENSDLDFEISG-FVSLPELTR-ANRNYIS 251
gi 1709188 199 NGN---G-DVRHVLAAIYGTAVAKKMLPL--HVSSLDFEVKG-YIALPEITR-ASRNYMS 250

                      130       140       150       160       170       180
               ....*....|....*....|....*....|....*....|....*....|....*....|
consensus  112 LFINGRPVEDKLLLKAIREVYATYLPRGRYPVFVLNLELPPELVDVNVHPDKKEVRLLKE 171
query      260 LFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHE 319
1B63_A     258 CYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQS 317
gi 8039787 270 TFVNGRRIFDYGLVQALVLGSEGYFPNGTFPVACLFLTVNSERIDFNIHPAKKEVHLQDY 329
gi 8928214 251 TFVNRRPIDQKDLLEAITNGHSRILSPGNFPICYLFLEINPEYIDFNVHPQKKEVRFYNL 310
gi 3914081 242 VFINKRPIQNKNLKEFLRKVFG------YKTLVVLYAELPPFMVDFNVHPKKKEVNILKE 295
gi 3914082 242 LFVNSRPVYNKNLKEYLKKTFG------YKTIVVLFIDIPPFLVDFNVHPKKKEVKFLKE 295
gi 8928224 250 FYVNGRFVVSEELHEVLMKVYD--LPKRSYPVAVLFIEVNPEELDVNIHPSKIVVKFLNE 307
gi 123083  252 LFINGRYIKNFLLNRAILDGFGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKE 311
gi 1709188 251 SVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKE 310


               ....*...
consensus  172 EEILDLIK 179
query      320 ESILERVQ 327
1B63_A     318 RLVHDFIY 325
gi 8039787 330 AHIRHTLS 337
gi 8928214 311 PFLFKLIS 318
gi 3914081 296 RKFLELVR 303
gi 3914082 296 RKIYELIR 303
gi 8928224 308 EKVKKSLE 315
gi 123083  312 KELMTLVS 319
gi 1709188 311 TELHDLIR 318