SOME FUNCTION of PROTEIN Z

Protein Z is a protein discovered by Sho-Hsieh. Althought there is no sequence homology to other proteins. I identify some function for this protein by finding homology to some domains of other proteins, and show below.

      

1. LIM-DOMAIN

(Matching pattern PS00478) 148: CSGCGRQIQDRFYLSAVEKRWHASCLQCYACRQPL 210: CSRCLASISSNELVMRARNLVFHVNCFCCTVCHTPL REFERENCE Structure of The Carboxy- Terminal Lim Domain from The Cystein Rich Protein CRP. G. C. Perez- alvarado, C. Miles, J. W. Michelsen, H. A Louis, D. R. Winge, M. C. Beckerle, M. F. Summers. Nat. Struct. Biol. , 1: 388 (1994)

    

2. CYTOCHROME-C

(Matching pattern PS00190) 238: CTVCHT REFERENCE 1 Structure of Rice Ferricytochrome C at 2.0 Angstroms Resolution. H. Ochi, Y. Hata, N. Tanaka, M. Kakudo, T. Sakurai, S. Aihara, Y. Morita. J. Mol. Biol. ,166: 407 (1983) REFERENCE 2 Amino Acid Sequence of Cytochrome C from Rice. E. Mori, Y. Morita. J. Biochem. (Tokyo), 87: 249 (1980)
    

    

3. IG-MHC

(Matching pattern PS00290) 236: FCCTVCH REFERENCE Emerging Principles for The Recognition of Peptide Antigens by MHC Class I Molecules. M. Matsumura, D. H. Fremont, P. A. Peterson, I. A. Wilson.Science, 257 : 927 (1992)