PROSITE: PDOC00516 (documentation)
{PDOC00516}
{PS00597; PLANT_LTP}
{BEGIN}
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* Plant lipid transfer proteins signature *
*******************************************
Plant cells contain proteins, called lipid transfer proteins (LTP) [1,2,3],
which are able to facilitate the transfer of phospholipids and other lipids
across membranes. These proteins, whose subcellular location is not yet known,
could play a major role in membrane biogenesis by conveying phospholipids
such as waxes or cutin from their site of biosynthesis to membranes unable to
form these lipids.
Plant LTP's are proteins of about 9 Kd (90 amino acids) which contain eight
conserved cysteine residues all involved in disulfide bridges, as shown in
the following schematic representation.
+-----------------------+
| +------+ |
| | | | ****************
xCxxxxCxxxxxxCCxxxxxxxxCxCxxxxxxxxxxxCxxxxxxCxx
| | | |
+--------|-------------+ |
+--------------------+
'C': conserved cysteine involved in a disulfide bond.
'*': position of the pattern.
-Consensus pattern: [LIVM]-[PA]-x(2)-C-x-[LIVM]-x-[LIVM]-x-[LIVMFY]-x-[LIVM]-
[ST]-x(3)-[DN]-C-x(2)-[LIVM]
[The two C's are involved in disulfide bonds]
-Sequences known to belong to this class detected by the pattern: ALL, except
for 5 sequences.
-Other sequence(s) detected in SWISS-PROT: NONE.
-Note: some of these proteins were originally thought to be alpha-amylase/
protease inhibitors (PAPI).
-Last update: November 1997 / Pattern and text revised.
[ 1] Wirtz K.W.A.
Annu. Rev. Biochem. 60:73-99(1991).
[ 2] Arondel V., Kader J.C.
Experientia 46:579-585(1990).
[ 3] Ohlrogge J.B., Browse J., Somerville C.R.
Biochim. Biophys. Acta 1082:1-26(1991).
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{END}