Homework 7-1

(1)sp|Q02454|CX1_NAJSP CARDIOTOXIN PRECURSOR pir||A44335 cardiotoxin - Naja naja gi|213375 (L04640) cardiotoxin [Naja naja]

Length = 81 Score = 340 (163.9 bits), Expect = 1.2e-44, P = 1.2e-44 Identities = 60/60 (100%), Positives = 60/60 (100%)

(2)sp|P01444|CX3_NAJAT CYTOTOXIN 3 PRECURSOR (CARDIOTOXIN ANALOGUE III) (CTX III) (CARDIOTOXIN C-10) (CYTOTOXIN IV) gi|1326091 (U42585) cardiotoxin III [Naja atra] gi|1661030 (U58486) cardiotoxin 3' [Naja atra]

Length = 81 Score = 340 (163.9 bits), Expect = 1.2e-44, P = 1.2e-44 Identities = 60/60 (100%), Positives = 60/60 (100%)

(3)pir||H3NJ3F cytotoxin 3 - Chinese cobra pir||JK0222 cytotoxin 10 - monocled cobra pir||B40667 cardiotoxin isoform 3, cytotoxin isoform 3, CTX-3 - Naja naja gi|299269 cardiotoxin isoform 3, cytotoxin isoform 3, CTX-3 [Naja naja=Formosan cobra, ssp. atra, venom, Peptide, 60 aa] pdb|2CRS| Cardiotoxin Iii (Nmr, 13 Structures) pdb|2CRT| Cardiotoxin Iii (Nmr, Minimized Average Structure) prf||0406231A toxin,cardio [Naja atra]

Length = 60 Score = 340 (163.9 bits), Expect = 1.6e-44, P = 1.6e-44 Identities = 60/60 (100%), Positives = 60/60 (100%)

Accession: Q02454 CARDIOTOXIN PRECURSOR. Length = 81 Score = 340 (163.9 bits) Expect = 3.4e-45 P = 3.4e-45 Identities = 60/60 (100%) Positives = 60/60 (100%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN

Subject: 22 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 81

Accession: P01444 CYTOTOXIN 3 PRECURSOR (CARDIOTOXIN ANALOGUE III) (CTX III) (CARDIOTOXIN C-10) (CYTOTOXIN IV). Length = 81 Score = 340 (163.9 bits) Expect = 3.4e-45 P = 3.4e-45 Identities = 60/60 (100%) Positives = 60/60 (100%)

Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN Subject: 22 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 81

Accession: P01440 CYTOTOXIN 2 (CYTOTOXIN II). Length = 60 Score = 331 (159.6 bits) Expect = 9.2e-44 P = 9.2e-44 Identities = 57/60 (95%) Positives = 60/60 (100%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKLVPLFYKTCPAGKNLCYKM+MVATPKVPVKRGCIDVCPKSSL++KYVCCNTDRCN Subject: 1 LKCNKLVPLFYKTCPAGKNLCYKMYMVATPKVPVKRGCIDVCPKSSLVLKYVCCNTDRCN 60

Accession: P24779 CYTOTOXIN 5 (CYTOTOXIN II). Length = 60 Score = 319 (153.8 bits) Expect = 5.1e-42 P = 5.1e-42 Identities = 55/60 (91%) Positives = 57/60 (95%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKL+PL YKTCPAGKNLCYKMFMVA PKVPVKRGCID CPK+SLLVKYVCCNTDRCN Subject: 1 LKCNKLIPLAYKTCPAGKNLCYKMFMVAAPKVPVKRGCIDACPKNSLLVKYVCCNTDRCN 60

Accession: P07525 CYTOTOXIN 5 (CARDIOTOXIN T) (CTX5) (CYTOTOXIN D1) (MEMBRANE TOXIN D1). Length = 60 Score = 318 (153.3 bits) Expect = 7.1e-42 P = 7.1e-42 Identities = 56/60 (93%) Positives = 57/60 (95%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKLVPLFYKTCPAGKNLCYKMFMV+ VPVKRGCIDVCPKSSLLVKYVCCNTDRCN Subject: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVSNKMVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60

Accession: P49124 CYTOTOXIN N PRECURSOR (CARDIOTOXIN N) (CTXN). Length = 81 Score = 315 (151.9 bits) Expect = 1.4e-41 P = 1.4e-41 Identities = 55/60 (91%) Positives = 57/60 (95%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCN+L+P FYKTC AGKNLCYKMFMVA PKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN Subject: 22 LKCNQLIPPFYKTCAAGKNLCYKMFMVAAPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 81

Accession: P80245 CYTOTOXIN 6 (CARDIOTOXIN 6) (CTX6). Length = 60 Score = 315 (151.9 bits) Expect = 1.9e-41 P = 1.9e-41 Identities = 55/60 (91%) Positives = 57/60 (95%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCN+L+P FYKTC AGKNLCYKMFMVA PKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN Subject: 1 LKCNQLIPPFYKTCAAGKNLCYKMFMVAAPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60

Accession: P01441 CYTOTOXIN 2. Length = 60 Score = 311 (150.0 bits) Expect = 7.3e-41 P = 7.3e-41 Identities = 55/60 (91%) Positives = 56/60 (93%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKC KLVPLF KTCPAGKNLCYKMFMVA P VPVKRGCIDVCPKSSLLVKYVCCNTD+CN Subject: 1 LKCKKLVPLFSKTCPAGKNLCYKMFMVAAPHVPVKRGCIDVCPKSSLLVKYVCCNTDKCN 60 Accession: P01442 CYTOTOXIN 2 (CARDIOTOXIN ANALOGUE II) (CTX2). Length = 60 Score = 308 (148.5 bits) Expect = 2.0e-40 P = 2.0e-40 Identities = 54/60 (90%) Positives = 56/60 (93%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKLVPLFYKTCPAGKNLCYKMFMV+ VPVKRGCIDVCPK+S LVKYVCCNTDRCN Subject: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVSNLTVPVKRGCIDVCPKNSALVKYVCCNTDRCN 60

Accession: P01445 CYTOTOXIN 2 (CYTOTOXIN CM-7A). Length = 60 Score = 306 (147.6 bits) Expect = 3.9e-40 P = 3.9e-40 Identities = 53/60 (88%) Positives = 56/60 (93%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKL+PL YKTCPAGKNLCYKMFMV+ VPVKRGCIDVCPK+SLLVKYVCCNTDRCN Subject: 1 LKCNKLIPLAYKTCPAGKNLCYKMFMVSNKTVPVKRGCIDVCPKNSLLVKYVCCNTDRCN 60

Accession: P49123 CYTOTOXIN 8 PRECURSOR (CARDIOTOXIN 8) (CTX8). Length = 81 Score = 305 (147.1 bits) Expect = 4.0e-40 P = 4.0e-40 Identities = 53/60 (88%) Positives = 56/60 (93%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCN+L+P FYK C AGKNLCYKMFMVA PKVPVKRGCIDVCPKSSLLVKYVCCNTDRC+ Subject: 22 LKCNQLIPPFYKACAAGKNLCYKMFMVAAPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCS 81

Accession: P01443 CYTOTOXIN 4 (CARDIOTOXIN ANALOGUE IV) (CTX-4). Length = 60 Score = 304 (146.6 bits) Expect = 7.6e-40 P = 7.6e-40 Identities = 53/59 (89%) Positives = 55/59 (93%) Query: 2 KCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 KCNKLVPLFYKTCPAGKNLCYKMFMV+ VPVKRGCIDVCPK+S LVKYVCCNTDRCN Subject: 2 KCNKLVPLFYKTCPAGKNLCYKMFMVSNLTVPVKRGCIDVCPKNSALVKYVCCNTDRCN 60

Accession: P01446 CYTOTOXIN 3 (CYTOTOXIN CM-7). Length = 60 Score = 302 (145.6 bits) Expect = 1.5e-39 P = 1.5e-39 Identities = 52/60 (86%) Positives = 55/60 (91%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKL+PL YKTCPAGKNLCYKMFMV+ VPVKRGCID CPK+SLLVKYVCCNTDRCN Subject: 1 LKCNKLIPLAYKTCPAGKNLCYKMFMVSNKTVPVKRGCIDACPKNSLLVKYVCCNTDRCN 60

Accession: P24780 CYTOTOXIN 3 (CYTOTOXIN IIA). Length = 60 Score = 300 (144.7 bits) Expect = 2.9e-39 P = 2.9e-39 Identities = 51/60 (85%) Positives = 56/60 (93%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKL+PL YKTCPAGKNLCYKMFMV+ VPVKRGCIDVCPK+SL++KYVCCNTDRCN Subject: 1 LKCNKLIPLAYKTCPAGKNLCYKMFMVSNKTVPVKRGCIDVCPKNSLVLKYVCCNTDRCN 60 Accession: P01451 CYTOTOXIN 1. Length = 60 Score = 293 (141.3 bits) Expect = 3.0e-38 P = 3.0e-38 Identities = 50/60 (83%) Positives = 55/60 (91%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKLVP+ YKTCP GKNLCYKMFM++ +PVKRGCIDVCPK+SLLVKYVCCNTDRCN Subject: 1 LKCNKLVPIAYKTCPEGKNLCYKMFMMSDLTIPVKRGCIDVCPKNSLLVKYVCCNTDRCN 60

Accession: P01447 CYTOTOXIN 1 (CYTOTOXIN XI). Length = 60 Score = 291 (140.3 bits) Expect = 5.9e-38 P = 5.9e-38 Identities = 49/60 (81%) Positives = 55/60 (91%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKL+PL YKTCPAGKNLCYKM+MV+ VPVKRGCIDVCPK+SL++KY CCNTDRCN Subject: 1 LKCNKLIPLAYKTCPAGKNLCYKMYMVSNKTVPVKRGCIDVCPKNSLVLKYECCNTDRCN 60

Accession: P01462 CYTOTOXIN 2 (TOXINS V-II-2 AND V-II-2A). Length = 60 Score = 291 (140.3 bits) Expect = 5.9e-38 P = 5.9e-38 Identities = 49/60 (81%) Positives = 55/60 (91%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKC+KLVP F+KTCP GKNLCYKM+MVATP +PVKRGCIDVCPK S LVKY+CCNTD+CN Subject: 1 LKCHKLVPPFWKTCPEGKNLCYKMYMVATPMLPVKRGCIDVCPKDSALVKYMCCNTDKCN 60

Accession: P01448 CYTOTOXIN 1 (CYTOTOXIN V-II-1). Length = 60 Score = 290 (139.8 bits) Expect = 8.2e-38 P = 8.2e-38 Identities = 49/60 (81%) Positives = 56/60 (93%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 L+CNKLVP+ +KTCPAGKNLCY+M+MV+ +PVKRGCIDVCPKSSLLVKYVCCNTDRCN Subject: 1 LECNKLVPIAHKTCPAGKNLCYQMYMVSKSTIPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60

Accession: P01454 CYTOTOXIN 9 (TOXIN CM-2E). Length = 60 Score = 290 (139.8 bits) Expect = 8.2e-38 P = 8.2e-38 Identities = 50/60 (83%) Positives = 54/60 (90%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 L+CNKLVP+ +KTCP GKNLCYKMFMV+T VPVKRGCIDVCPK S LVKYVCCNTDRCN Subject: 1 LECNKLVPIAHKTCPEGKNLCYKMFMVSTSTVPVKRGCIDVCPKDSALVKYVCCNTDRCN 60

Accession: P01463 CYTOTOXIN 2 (TOXIN V-II-2). Length = 60 Score = 289 (139.4 bits) Expect = 1.1e-37 P = 1.1e-37 Identities = 47/60 (78%) Positives = 56/60 (93%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKC++L+P F+KTCP GKNLCYKM+MVATP +PVKRGCIDVCPK+S LVKY+CCNTD+CN Subject: 1 LKCHQLIPPFWKTCPEGKNLCYKMYMVATPMIPVKRGCIDVCPKNSALVKYMCCNTDKCN 60

Accession: P01464 CYTOTOXIN 5 (TOXIN CM-6). Length = 60 Score = 289 (139.4 bits) Expect = 1.1e-37 P = 1.1e-37 Identities = 48/60 (80%) Positives = 56/60 (93%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKC+KLVP F+KTCP GKNLCYKM+MVATP +PVKRGCIDVCPK+S LVKY+CCNT++CN Subject: 1 LKCHKLVPPFWKTCPEGKNLCYKMYMVATPMIPVKRGCIDVCPKNSALVKYMCCNTNKCN 60

Accession: P01449 CYTOTOXIN 1 PRECURSOR (CARDIOTOXIN F8) (CYTOTOXIN CM-6) (CARDIOTOXIN- ANALOGUE I) (CTX I) (CTX1). Length = 81 Score = 288 (138.9 bits) Expect = 1.2e-37 P = 1.2e-37 Identities = 49/60 (81%) Positives = 55/60 (91%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKL+P+ KTCPAGKNLCYKMFM++ +PVKRGCIDVCPK+SLLVKYVCCNTDRCN Subject: 22 LKCNKLIPIASKTCPAGKNLCYKMFMMSDLTIPVKRGCIDVCPKNSLLVKYVCCNTDRCN 81

Accession: P01453 CYTOTOXIN 10 (TOXIN CM-4A). Length = 60 Score = 286 (137.9 bits) Expect = 3.1e-37 P = 3.1e-37 Identities = 48/60 (80%) Positives = 55/60 (91%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 L+CN+L+P+ +KTCP GKNLCYKMFMV+T VPVKRGCIDVCPK+S LVKYVCCNTDRCN Subject: 1 LECNQLIPIAHKTCPEGKNLCYKMFMVSTSTVPVKRGCIDVCPKNSALVKYVCCNTDRCN 60

Accession: P01465 CYTOTOXIN 6 (TOXIN CM-2H). Length = 60 Score = 286 (137.9 bits) Expect = 3.1e-37 P = 3.1e-37 Identities = 48/60 (80%) Positives = 55/60 (91%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKC+KLVP F+KTCP GKNLCYKM+MVATP +PVKRGCIDVCPK S LVKY+CCNT++CN Subject: 1 LKCHKLVPPFWKTCPEGKNLCYKMYMVATPMLPVKRGCIDVCPKDSALVKYMCCNTNKCN 60

Accession: P01468 CYTOTOXIN 1 (CARDIOTOXIN GAMMA). Length = 60 Score = 285 (137.4 bits) Expect = 4.4e-37 P = 4.4e-37 Identities = 48/60 (80%) Positives = 54/60 (90%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCN+L+P F+KTCP GKNLCYKM M A P VPVKRGCIDVCPKSSLL+KY+CCNTD+CN Subject: 1 LKCNQLIPPFWKTCPKGKNLCYKMTMRAAPMVPVKRGCIDVCPKSSLLIKYMCCNTDKCN 60

Accession: P01458 CYTOTOXIN 3 (TOXIN V-II-3). Length = 60 Score = 285 (137.4 bits) Expect = 4.4e-37 P = 4.4e-37 Identities = 48/60 (80%) Positives = 54/60 (90%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCN+L+P F+KTCP GKNLCY M+MV+T VPVKRGCIDVCPK+S LVKYVCCNTDRCN Subject: 1 LKCNQLIPPFWKTCPKGKNLCYNMYMVSTSTVPVKRGCIDVCPKNSALVKYVCCNTDRCN 60

Accession: P01461 CYTOTOXIN 4 (TOXIN CM-11). Length = 60 Score = 284 (136.9 bits) Expect = 6.1e-37 P = 6.1e-37 Identities = 48/60 (80%) Positives = 55/60 (91%) Query: 1 LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN 60 LKCNKL+P F+KTCP GKNLCYKM+MV+T VPVKRGCIDVCPK+S LVKYVCCNT++CN

[Image] Version 2.0 Sequence View SWISSPROT:CX2_NAJKA - OS NAJA NAJA KAOUTHIA (MONOCLED COBRA) (NAJA NAJA SIAMENSIS). >CX2_NAJKA LKCNKLIPLAYKTCPAGKNLCYKMFMVSNKTVPVKRGCIDVCPKNSLLVKYVCCNTDRCN ---------------------------------------------------------------------------- SWISSPROT:CX2_NAJAT - OS NAJA ATRA (CHINESE COBRA). >CX2_NAJAT LKCNKLVPLFYKTCPAGKNLCYKMFMVSNLTVPVKRGCIDVCPKNSALVKYVCCNTDRCN ---------------------------------------------------------------------------- SWISSPROT:CX2_NAJOX - OS NAJA OXIANA (CENTRAL ASIAN COBRA) (OXUS COBRA). >CX2_NAJOX LKCKKLVPLFSKTCPAGKNLCYKMFMVAAPHVPVKRGCIDVCPKSSLLVKYVCCNTDKCN ---------------------------------------------------------------------------- SWISSPROT:CX6_NAJAT - OS NAJA ATRA (CHINESE COBRA). >CX6_NAJAT LKCNQLIPPFYKTCAAGKNLCYKMFMVAAPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN ---------------------------------------------------------------------------- SWISSPROT:CXN_NAJAT - OS NAJA ATRA (CHINESE COBRA). >CXN_NAJAT MKTLLLTLVVATIVCLDLGYTLKCNQLIPPFYKTCAAGKNLCYKMFMVAAPKVPVKRGCI DVCPKSSLLVKYVCCNTDRCN ---------------------------------------------------------------------------- SWISSPROT:CX5_NAJAT - OS NAJA ATRA (CHINESE COBRA). >CX5_NAJAT LKCNKLVPLFYKTCPAGKNLCYKMFMVSNKMVPVKRGCIDVCPKSSLLVKYVCCNTDRCN ---------------------------------------------------------------------------- SWISSPROT:CX5_NAJKA - OS NAJA NAJA KAOUTHIA (MONOCLED COBRA) (NAJA NAJA SIAMENSIS). >CX5_NAJKA LKCNKLIPLAYKTCPAGKNLCYKMFMVAAPKVPVKRGCIDACPKNSLLVKYVCCNTDRCN ---------------------------------------------------------------------------- SWISSPROT:CX2_NAJNA - OS NAJA NAJA (INDIAN COBRA). >CX2_NAJNA LKCNKLVPLFYKTCPAGKNLCYKMYMVATPKVPVKRGCIDVCPKSSLVLKYVCCNTDRCN ---------------------------------------------------------------------------- SWISSPROT:CX3_NAJAT - OS NAJA ATRA (CHINESE COBRA), AND NAJA NAJA KAOUTHIA (MONOCLED >CX3_NAJAT MKTLLLTLVVVTIVCLDLGYTLKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCI DVCPKSSLLVKYVCCNTDRCN ---------------------------------------------------------------------------- SWISSPROT:CX1_NAJSP - OS NAJA SPUTATRIX (MALAYAN SPITTING COBRA). >CX1_NAJSP MKTLLLTTVVVTIVCLDLEYTLKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCI DVCPKSSLLVKYVCCNTDRCN