HOMEWORK#3


The X-ray structure of the same protein in homework 2 from a different organism (human) has been solved. It is a complex structure with DNA.
1.Which journal did authors publish the structure of this protein ? Please also give its abstract.
[ANS]

2. Please find the structure in Protein Data Bank.

(A) Give the PDB ID # of this structure.
(B) How many residues of this protein that shown in the structure?
(C) What is the DNA sequence in the complex structure? [ANS]
    3. Give two rasmol pictures of the structure. One with DNA, one without. [ANS]

    4. Identify the basic residues that contact DNA. Measure the distance between these residues and corresponding DNA bases (potential H-bond partner).

      (A) List these residues, corresponding bases and distance in a table.
      (B) Please label these residue in a picture. [ANS]
       

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