assignment7
1. Search human Mlh1 or its homologous proteins in Protein Data Bank (PDB) database. You just need to search for protein structure, do not find complex structure. Give its (a) ID number, (b) Name of the molecule, (c) experimental method for structure determination and (d) Resolution of the structure.
| (a) ID number: | 1EWR |
| (b) Name of the molecule: | DNA Mismatch Repair Protein Muts |
| (c) experimental method for structure dete: | X-ray Diffraction |
| (d) Resolution of the structure:rmination: | 3.19 |
2. Show its structure in ribbons form (400x400).
¦³Ánµ³á!
3. Give the structural informations of this
PDB file (a) number of protein chains, (b) number of helix in one protein chain,
(c) the first and last residues in the helix 6 .
| (a) number of protein chains | 2 |
| (b) number of helix in one protein chain |
A chain:19¡@¡@¡@B chain:22 |
| (c)
the first and last residues in the helix 6 |
first: proline ¡@last: leucine |
4. Give the Class, Fold, Superfamily and Family of this protein in Structural Classification of Proteins (SCOP).
| Class | All alpha proteins |
| Fold | DNA repair protein MutS, domain III |
| Superfamily | DNA repair protein MutS, domain III |
| Family | DNA repair protein MutS, domain III |
| Class | Alpha and beta proteins (a/b) |
| Fold | P-loop containing nucleotide triphosphate hydrolases |
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Family | ABC transporter ATPase domain-like |
| Class | Alpha and beta proteins (a/b) |
| Fold | Ribonuclease H-like motif |
| Superfamily | DNA repair protein MutS, domain II |
| Family | DNA repair protein MutS, domain II |
5. (a) Show Ramachandran
plot for this PDB file. (b) How many residues are in the most favoured regions
of Ramachandran plot?
(a) Show Ramachandran plot for this PDB file
(b) How many residues are in the most favoured regions of Ramachandran plot?
646