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HomoloGene
 
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HomoloGene

Title of analyzed group and its possible orthologs:



Human MLH1mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2)
UniGene Cluster: Hs.57301
LocusLink 4292 MLH1
MouseHmga1 high mobility group AT-hook 1
UniGene Cluster: Mm.4438
LocusLink 15361 Hmga1
Cow- ESTs, Moderately similar to 2007430A DNA mismatch repair protein [H.sapiens]
UniGene Cluster: Bt.5658
FlyCG14964
LocusLink 38384 CG14964


CURATED ORTHOLOGS
Published orthologs as reported in curated databases
more info
  Human
Hs.57301
LocusLink 4292 MLH1
Homology map
Mm
Hs
Mm.196006
LocusLink 17350 Mlh1

Mouse


CALCULATED ORTHOLOGS
Listed below are UniGene clusters which are possible orthologs as determined by nucleotide sequence comparisons.
more info

OrganismSequence % ID Sequence Organism
  Rat
Rn.20391
U80054
LocusLink 81685 Mlh1
87.1
reciprocal best hit
Bt.5658
BF889707

Cow
  Mouse
Mm.196006
AF250844
LocusLink 17350 Mlh1
87.4
reciprocal best hit
Bt.5658
BE682763

Cow
  Mouse
Mm.4438
J04179
LocusLink 15361 Hmga1
87.5
reciprocal best hit
Bt.4044
BE681647

Cow
  Human
Hs.57301
BC005866
LocusLink 4292 MLH1
90.5
reciprocal best hit
Mm.4438
AK010617
LocusLink 15361 Hmga1

Mouse
  Human
Hs.57301
U07418
LocusLink 4292 MLH1
90.7
reciprocal best hit
Bt.5658
BF889707

Cow
  Human
Hs.57301
BE902010
LocusLink 4292 MLH1
70.2
reciprocal best hit
LocusLink 38384 CG14964

Fly
  Mouse
Mm.4438
AK010617
LocusLink 15361 Hmga1
98.2
reciprocal best hit
Rn.65636
BG153354

Rat
  Mouse
Mm.23949
AK004105
LocusLink 68687 1110035C23Rik
87.4
reciprocal best hit
Bt.5658
BE682763

Cow
  Human
Hs.57301
BC005866
LocusLink 4292 MLH1
92.0
has a best hit coming from it to
Rn.3123
BF566744

Rat
  Human
Hs.57301
U07343
LocusLink 4292 MLH1
89.3
has a best hit coming to it from
Rn.20391
U80054
LocusLink 81685 Mlh1

Rat
  Human
Hs.57301
U07418
LocusLink 4292 MLH1
89.3
has a best hit coming to it from
Mm.23949
AK004105
LocusLink 68687 1110035C23Rik

Mouse
  Human
Hs.57301
U07343
LocusLink 4292 MLH1
89.3
has a best hit coming to it from
Mm.196006
AF250844
LocusLink 17350 Mlh1

Mouse
  Human
Hs.57301
BG823070
LocusLink 4292 MLH1
68.8
has a best hit coming from it to
Dr.10383
BE605992

Zebrafish
  Human
Hs.57301
BG751839
LocusLink 4292 MLH1
64.0
has a best hit coming to it from
Dr.2921
AI793613

Zebrafish
  Human
Hs.57301
AW967987
LocusLink 4292 MLH1
69.8
has a best hit coming from it to
Xl.2114
BG347757

Frog
  Human
Hs.57301
AU127122
LocusLink 4292 MLH1
67.0
has a best hit coming from it to
LocusLink 41330 BcDNAGH05741

Fly
  Human
Hs.57301
BG201774
LocusLink 4292 MLH1
65.4
has a best hit coming from it to
LocusLink 37112 CG17531

Fly
reciprocal best hitA double headed arrow indicates that the pair represents a reciprocal best hit, the match is the best one for both organisms.
from or toA single headed arrow indicates that the pair represents the best match for one of the organisms. The direction of the arrow indicates whether it is from or to the corresponding organism.
tripletWhen present, red arrows point out a group of sequence matches which are part of a triplet, being consistent between more than two organisms.





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