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Various functions are found in helical proteins. Other important helical protein such as Jun and Fos are transcription regulating protein. The helical shape provides a good binding mechanism. For instance, the dimerization of Jun and Fos can initiate the binding on the transcription domain of DNA. Other leucine-zipper and helix-turn-helix factors also have these kind of helical recognition domain. Yet, SNARE is different from those transcription factors.