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231041 ---------------------------------------------------
Definition Insulin
PDB Molecule: 4INS, Chain: D
NCBI Seq ID: 231041
Comment 3-D Structure determined by X-Ray Diffraction
Class: Hormone
Source: Pig (Sus scrofa)
Comment Revision History:
JUL 31 94 Coordinates
JUL 15 93 Typographical
APR 15 90 Initial Entry
Citation Data Submission: G.G.Dodson, E.J.Dodson, D.C.Hodgkin,
N.W.Isaacs & M.Vijayan (1989).
Citation E.N.Baker, T.L.Blundell, J.F.Cutfield, S.M.Cutfield,
E.J.Dodson, G.G.Dodson, D.M.Crowfoot Hodgkin, R.E.Hubbard,
N.W.Isaacs, C.D.Reynolds, K.Sakabe, N.Sakabe & N.M.Vijayan
(1988). The structure of 2Zn pig insulin crystals at 1.5 A
resolution. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 319,
369-456.
MEDLINE identifier: 89099318
Citation J.Bordas, G.G.Dodson, H.Grewe, M.H.J.Koch, B.Krebs & J.Randall
(1983). A Comparative Assessment Of The Zinc-Protein
Coordination In 2Zn-Insulin As Determined By X-Ray Absorption
Fine Structure (EXAFS) And X-Ray Crystallography.
Proc.R.Soc.London,Ser.B 219, 21.
Citation E.J. Dodson, G.G. Dodson, D.C. Hodgkin & C.D. Reynolds (1979).
Structural relationships in the two-zinc insulin hexamer.
Can. J. Biochem. 57, 469-479.
MEDLINE identifier: 80001323
Citation N.W.Isaacs & R.C.Agarwal (1978). Experience With Fast Fourier
Least Squares In The Refinement Of The Crystal Structure Of
Rhombohedral 2-Zinc Insulin At 1.5 Angstroms Resolution. Acta
Crystallogr.,Sect.A 34, 782.
Citation G. Bentley, G. Dodson & A. Lewitova (1978). Rhombohedral
insulin crystal transformation. J. Mol. Biol. 126, 871-875.
MEDLINE identifier: 79132592
Citation E.J.Dodson, N.W.Isaacs & J.S.Rollett (1976). A Method For
Fitting Satisfactory Models To Sets Of Atomic Positions In
Protein Structure Refinements. Acta Crystallogr.,Sect.A 32,
311.
Citation D.C.Hodgkin (1974). Varieties Of Insulin. J.Endocrinol. 63,
1.
Citation D.C. Hodgkin (1972). The structure of insulin. Dan Tidsskr
Farm 46, 1-28.
MEDLINE identifier: 72164661
Citation T.Blundell, G.Dodson, D.Hodgkin & D.Mercola (1972). Insulin.
The Structure In The Crystal And Its Reflection In Chemistry
And Biology. Adv.Protein Chem. 26, 279.
Citation T.L. Blundell, J.F. Cutfield, E.J. Dodson, G.G. Dodson, D.C.
Hodgkin & D.A. Mercola (1972). The crystal structure of
rhombohedral 2 zinc insulin. Cold Spring Harb. Symp. Quant.
Biol. 36, 233-241.
MEDLINE identifier: 73041131
Citation T.L. Blundell, J.F. Cutfield, S.M. Cutfield, E.J. Dodson, G.G.
Dodson, D.C. Hodgkin, D.A. Mercola & M. Vijayan (1971).
Atomic positions in rhombohedral 2-zinc insulin crystals.
Nature 231, 506-511.
MEDLINE identifier: 71230365
Citation T.L. Blundell, G.G. Dodson, E. Dodson, D.C. Hodgkin & M.
Vijayan (1971). X-ray analysis and the structure of insulin.
Recent Prog. Horm. Res. 27, 1-40.
MEDLINE identifier: 72115099
Citation E.N. Baker & G. Dodson (1970). X-ray diffraction data on some
crystalline varieties of insulin. J. Mol. Biol. 54, 605-609.
MEDLINE identifier: 71077285
Citation M.J.Adams, T.L.Blundell, E.J.Dodson, G.G.Dodson, M.Vijayan,
E.N.Baker, M.M.Harding, D.C.Hodgkin, B.Rimmer & S.Sheat
(1969). Structure Of Rhombohedral 2 Zinc Insulin Crystals.
Nature 224, 491.
Citation Atlas Of Protein Sequence And Structure (Data Section) (1972);
M.O.Dayhoff; National Biomedical Research Foundation, Silver
Spring,Md.; 187.
Sec. Str. Helix 4INS_D: 8..19
helix 3
Heterogen ( ZN, 2 ) Zinc Ion On 3-Fold 4INS_D: 10 bond
Crystal Axis
Sequence 30 aa
1 fvnqhlcgsh lvealylvcg ergffytpka
Views:
Links:
231040 ---------------------------------------------------
Definition Insulin
PDB Molecule: 4INS, Chain: C
NCBI Seq ID: 231040
Comment 3-D Structure determined by X-Ray Diffraction
Class: Hormone
Source: Pig (Sus scrofa)
Comment Revision History:
JUL 31 94 Coordinates
JUL 15 93 Typographical
APR 15 90 Initial Entry
Citation Data Submission: G.G.Dodson, E.J.Dodson, D.C.Hodgkin,
N.W.Isaacs & M.Vijayan (1989).
Citation E.N.Baker, T.L.Blundell, J.F.Cutfield, S.M.Cutfield,
E.J.Dodson, G.G.Dodson, D.M.Crowfoot Hodgkin, R.E.Hubbard,
N.W.Isaacs, C.D.Reynolds, K.Sakabe, N.Sakabe & N.M.Vijayan
(1988). The structure of 2Zn pig insulin crystals at 1.5 A
resolution. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 319,
369-456.
MEDLINE identifier: 89099318
Citation J.Bordas, G.G.Dodson, H.Grewe, M.H.J.Koch, B.Krebs & J.Randall
(1983). A Comparative Assessment Of The Zinc-Protein
Coordination In 2Zn-Insulin As Determined By X-Ray Absorption
Fine Structure (EXAFS) And X-Ray Crystallography.
Proc.R.Soc.London,Ser.B 219, 21.
Citation E.J. Dodson, G.G. Dodson, D.C. Hodgkin & C.D. Reynolds (1979).
Structural relationships in the two-zinc insulin hexamer.
Can. J. Biochem. 57, 469-479.
MEDLINE identifier: 80001323
Citation N.W.Isaacs & R.C.Agarwal (1978). Experience With Fast Fourier
Least Squares In The Refinement Of The Crystal Structure Of
Rhombohedral 2-Zinc Insulin At 1.5 Angstroms Resolution. Acta
Crystallogr.,Sect.A 34, 782.
Citation G. Bentley, G. Dodson & A. Lewitova (1978). Rhombohedral
insulin crystal transformation. J. Mol. Biol. 126, 871-875.
MEDLINE identifier: 79132592
Citation E.J.Dodson, N.W.Isaacs & J.S.Rollett (1976). A Method For
Fitting Satisfactory Models To Sets Of Atomic Positions In
Protein Structure Refinements. Acta Crystallogr.,Sect.A 32,
311.
Citation D.C.Hodgkin (1974). Varieties Of Insulin. J.Endocrinol. 63,
1.
Citation D.C. Hodgkin (1972). The structure of insulin. Dan Tidsskr
Farm 46, 1-28.
MEDLINE identifier: 72164661
Citation T.Blundell, G.Dodson, D.Hodgkin & D.Mercola (1972). Insulin.
The Structure In The Crystal And Its Reflection In Chemistry
And Biology. Adv.Protein Chem. 26, 279.
Citation T.L. Blundell, J.F. Cutfield, E.J. Dodson, G.G. Dodson, D.C.
Hodgkin & D.A. Mercola (1972). The crystal structure of
rhombohedral 2 zinc insulin. Cold Spring Harb. Symp. Quant.
Biol. 36, 233-241.
MEDLINE identifier: 73041131
Citation T.L. Blundell, J.F. Cutfield, S.M. Cutfield, E.J. Dodson, G.G.
Dodson, D.C. Hodgkin, D.A. Mercola & M. Vijayan (1971).
Atomic positions in rhombohedral 2-zinc insulin crystals.
Nature 231, 506-511.
MEDLINE identifier: 71230365
Citation T.L. Blundell, G.G. Dodson, E. Dodson, D.C. Hodgkin & M.
Vijayan (1971). X-ray analysis and the structure of insulin.
Recent Prog. Horm. Res. 27, 1-40.
MEDLINE identifier: 72115099
Citation E.N. Baker & G. Dodson (1970). X-ray diffraction data on some
crystalline varieties of insulin. J. Mol. Biol. 54, 605-609.
MEDLINE identifier: 71077285
Citation M.J.Adams, T.L.Blundell, E.J.Dodson, G.G.Dodson, M.Vijayan,
E.N.Baker, M.M.Harding, D.C.Hodgkin, B.Rimmer & S.Sheat
(1969). Structure Of Rhombohedral 2 Zinc Insulin Crystals.
Nature 224, 491.
Citation Atlas Of Protein Sequence And Structure (Data Section) (1972);
M.O.Dayhoff; National Biomedical Research Foundation, Silver
Spring,Md.; 187.
disulfide bond 4INS_C: 6 bond 11
Sequence 21 aa
1 giveqcctsi cslyqlenyc n
Views:
Links:
231039 ---------------------------------------------------
Definition Insulin
PDB Molecule: 4INS, Chain: B
NCBI Seq ID: 231039
Comment 3-D Structure determined by X-Ray Diffraction
Class: Hormone
Source: Pig (Sus scrofa)
Comment Revision History:
JUL 31 94 Coordinates
JUL 15 93 Typographical
APR 15 90 Initial Entry
Citation Data Submission: G.G.Dodson, E.J.Dodson, D.C.Hodgkin,
N.W.Isaacs & M.Vijayan (1989).
Citation E.N.Baker, T.L.Blundell, J.F.Cutfield, S.M.Cutfield,
E.J.Dodson, G.G.Dodson, D.M.Crowfoot Hodgkin, R.E.Hubbard,
N.W.Isaacs, C.D.Reynolds, K.Sakabe, N.Sakabe & N.M.Vijayan
(1988). The structure of 2Zn pig insulin crystals at 1.5 A
resolution. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 319,
369-456.
MEDLINE identifier: 89099318
Citation J.Bordas, G.G.Dodson, H.Grewe, M.H.J.Koch, B.Krebs & J.Randall
(1983). A Comparative Assessment Of The Zinc-Protein
Coordination In 2Zn-Insulin As Determined By X-Ray Absorption
Fine Structure (EXAFS) And X-Ray Crystallography.
Proc.R.Soc.London,Ser.B 219, 21.
Citation E.J. Dodson, G.G. Dodson, D.C. Hodgkin & C.D. Reynolds (1979).
Structural relationships in the two-zinc insulin hexamer.
Can. J. Biochem. 57, 469-479.
MEDLINE identifier: 80001323
Citation N.W.Isaacs & R.C.Agarwal (1978). Experience With Fast Fourier
Least Squares In The Refinement Of The Crystal Structure Of
Rhombohedral 2-Zinc Insulin At 1.5 Angstroms Resolution. Acta
Crystallogr.,Sect.A 34, 782.
Citation G. Bentley, G. Dodson & A. Lewitova (1978). Rhombohedral
insulin crystal transformation. J. Mol. Biol. 126, 871-875.
MEDLINE identifier: 79132592
Citation E.J.Dodson, N.W.Isaacs & J.S.Rollett (1976). A Method For
Fitting Satisfactory Models To Sets Of Atomic Positions In
Protein Structure Refinements. Acta Crystallogr.,Sect.A 32,
311.
Citation D.C.Hodgkin (1974). Varieties Of Insulin. J.Endocrinol. 63,
1.
Citation D.C. Hodgkin (1972). The structure of insulin. Dan Tidsskr
Farm 46, 1-28.
MEDLINE identifier: 72164661
Citation T.Blundell, G.Dodson, D.Hodgkin & D.Mercola (1972). Insulin.
The Structure In The Crystal And Its Reflection In Chemistry
And Biology. Adv.Protein Chem. 26, 279.
Citation T.L. Blundell, J.F. Cutfield, E.J. Dodson, G.G. Dodson, D.C.
Hodgkin & D.A. Mercola (1972). The crystal structure of
rhombohedral 2 zinc insulin. Cold Spring Harb. Symp. Quant.
Biol. 36, 233-241.
MEDLINE identifier: 73041131
Citation T.L. Blundell, J.F. Cutfield, S.M. Cutfield, E.J. Dodson, G.G.
Dodson, D.C. Hodgkin, D.A. Mercola & M. Vijayan (1971).
Atomic positions in rhombohedral 2-zinc insulin crystals.
Nature 231, 506-511.
MEDLINE identifier: 71230365
Citation T.L. Blundell, G.G. Dodson, E. Dodson, D.C. Hodgkin & M.
Vijayan (1971). X-ray analysis and the structure of insulin.
Recent Prog. Horm. Res. 27, 1-40.
MEDLINE identifier: 72115099
Citation E.N. Baker & G. Dodson (1970). X-ray diffraction data on some
crystalline varieties of insulin. J. Mol. Biol. 54, 605-609.
MEDLINE identifier: 71077285
Citation M.J.Adams, T.L.Blundell, E.J.Dodson, G.G.Dodson, M.Vijayan,
E.N.Baker, M.M.Harding, D.C.Hodgkin, B.Rimmer & S.Sheat
(1969). Structure Of Rhombohedral 2 Zinc Insulin Crystals.
Nature 224, 491.
Citation Atlas Of Protein Sequence And Structure (Data Section) (1972);
M.O.Dayhoff; National Biomedical Research Foundation, Silver
Spring,Md.; 187.
Sec. Str. Helix 4INS_B: 10..19
helix 2
Heterogen ( ZN, 1 ) Zinc Ion On 3-Fold 4INS_B: 10 bond
Crystal Axis
Sequence 30 aa
1 fvnqhlcgsh lvealylvcg ergffytpka
Views:
Links:
231038 ---------------------------------------------------
Definition Insulin
PDB Molecule: 4INS, Chain: A
NCBI Seq ID: 231038
Comment 3-D Structure determined by X-Ray Diffraction
Class: Hormone
Source: Pig (Sus scrofa)
Comment Revision History:
JUL 31 94 Coordinates
JUL 15 93 Typographical
APR 15 90 Initial Entry
Citation Data Submission: G.G.Dodson, E.J.Dodson, D.C.Hodgkin,
N.W.Isaacs & M.Vijayan (1989).
Citation E.N.Baker, T.L.Blundell, J.F.Cutfield, S.M.Cutfield,
E.J.Dodson, G.G.Dodson, D.M.Crowfoot Hodgkin, R.E.Hubbard,
N.W.Isaacs, C.D.Reynolds, K.Sakabe, N.Sakabe & N.M.Vijayan
(1988). The structure of 2Zn pig insulin crystals at 1.5 A
resolution. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 319,
369-456.
MEDLINE identifier: 89099318
Citation J.Bordas, G.G.Dodson, H.Grewe, M.H.J.Koch, B.Krebs & J.Randall
(1983). A Comparative Assessment Of The Zinc-Protein
Coordination In 2Zn-Insulin As Determined By X-Ray Absorption
Fine Structure (EXAFS) And X-Ray Crystallography.
Proc.R.Soc.London,Ser.B 219, 21.
Citation E.J. Dodson, G.G. Dodson, D.C. Hodgkin & C.D. Reynolds (1979).
Structural relationships in the two-zinc insulin hexamer.
Can. J. Biochem. 57, 469-479.
MEDLINE identifier: 80001323
Citation N.W.Isaacs & R.C.Agarwal (1978). Experience With Fast Fourier
Least Squares In The Refinement Of The Crystal Structure Of
Rhombohedral 2-Zinc Insulin At 1.5 Angstroms Resolution. Acta
Crystallogr.,Sect.A 34, 782.
Citation G. Bentley, G. Dodson & A. Lewitova (1978). Rhombohedral
insulin crystal transformation. J. Mol. Biol. 126, 871-875.
MEDLINE identifier: 79132592
Citation E.J.Dodson, N.W.Isaacs & J.S.Rollett (1976). A Method For
Fitting Satisfactory Models To Sets Of Atomic Positions In
Protein Structure Refinements. Acta Crystallogr.,Sect.A 32,
311.
Citation D.C.Hodgkin (1974). Varieties Of Insulin. J.Endocrinol. 63,
1.
Citation D.C. Hodgkin (1972). The structure of insulin. Dan Tidsskr
Farm 46, 1-28.
MEDLINE identifier: 72164661
Citation T.Blundell, G.Dodson, D.Hodgkin & D.Mercola (1972). Insulin.
The Structure In The Crystal And Its Reflection In Chemistry
And Biology. Adv.Protein Chem. 26, 279.
Citation T.L. Blundell, J.F. Cutfield, E.J. Dodson, G.G. Dodson, D.C.
Hodgkin & D.A. Mercola (1972). The crystal structure of
rhombohedral 2 zinc insulin. Cold Spring Harb. Symp. Quant.
Biol. 36, 233-241.
MEDLINE identifier: 73041131
Citation T.L. Blundell, J.F. Cutfield, S.M. Cutfield, E.J. Dodson, G.G.
Dodson, D.C. Hodgkin, D.A. Mercola & M. Vijayan (1971).
Atomic positions in rhombohedral 2-zinc insulin crystals.
Nature 231, 506-511.
MEDLINE identifier: 71230365
Citation T.L. Blundell, G.G. Dodson, E. Dodson, D.C. Hodgkin & M.
Vijayan (1971). X-ray analysis and the structure of insulin.
Recent Prog. Horm. Res. 27, 1-40.
MEDLINE identifier: 72115099
Citation E.N. Baker & G. Dodson (1970). X-ray diffraction data on some
crystalline varieties of insulin. J. Mol. Biol. 54, 605-609.
MEDLINE identifier: 71077285
Citation M.J.Adams, T.L.Blundell, E.J.Dodson, G.G.Dodson, M.Vijayan,
E.N.Baker, M.M.Harding, D.C.Hodgkin, B.Rimmer & S.Sheat
(1969). Structure Of Rhombohedral 2 Zinc Insulin Crystals.
Nature 224, 491.
Citation Atlas Of Protein Sequence And Structure (Data Section) (1972);
M.O.Dayhoff; National Biomedical Research Foundation, Silver
Spring,Md.; 187.
Sec. Str. Helix 4INS_A: 1..9
helix 1
disulfide bond 4INS_A: 6 bond 11
Sequence 21 aa
1 giveqcctsi cslyqlenyc n